The Surprising Link Between Weight Gain and Antidepressants

Antidepressants are powerful tools that can stabilize and improve mood and are important to take as directed when your provider prescribes them for you. However, in some cases, these medications may lead to unexpected weight gain. This doesn’t usually happen right away but often appears after several months of consistent use. Interestingly, some medications may even cause short-term weight loss initially. 

Why does weight gain happen with antidepressants? 

There are a few reasons why antidepressants can lead to weight gain: 

1. Increased Hunger: Antidepressants might make you feel hungrier. This could be because they help you feel less down or irritable, but some people simply experience a general boost in appetite. Often, this includes cravings for carb-heavy foods like bread and pasta.
2. Slower Metabolism: Some medications can slow down how your body burns calories by affecting glucose metabolism. This makes it easier to gain weight over time.
3. Medication Type: Certain antidepressants, mood stabilizers, and other prescriptions are more likely to cause weight gain. However, not everyone on these medications will have this side effect.
4. Age and Metabolism: As we get older, our metabolism naturally slows down. This, combined with medication, can make it easier to gain weight.

If you’re gaining weight while on antidepressants, talk to your primary care provider. They may want to monitor your blood pressure, cholesterol, and triglycerides. They might also suggest working with a nutritionist. Here are some tips to help manage your weight: 

1. Stay Active: Adults should aim for at least 150 minutes of moderate exercise each week. This should include activities like walking or weightlifting. Even small amounts of movement can make a difference.
2. Eat More Plants: Fill your plate with fruits and vegetables. Aim for at least 1.5 cups of fruit and 2-3 cups of veggies daily—more is even better.
3. Cut Processed Foods: Avoid fast food, processed food, and items with added sugars. Check labels to spot hidden sugar and limit refined carbs.
4. Include Lean Protein: Protein should make up 10% to 30% of your daily calories. Choose lean options like chicken, fish, or plant-based proteins.
5. Track Calories: Keeping an eye on your calorie intake can help prevent overeating.
6. Drink Water: Stay hydrated throughout the day.
7. Prioritize Sleep: Poor sleep can lead to overeating and low energy. If you snore, talk to your doctor about a possible sleep study, as sleep apnea can make weight management harder.

If these steps don’t help, reach out to your primary care provider for additional support. They can guide you toward solutions that work for your situation. 

William Charmak, PhD, ABPP is in practice at Foundation Counselling and Wellness. 








 

Amy Rose, PMHNP-BC, APRN is in practice at Foundation Collaborative Care.